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classical complement pathway

PAG Title classical complement pathway
PAG ID WAG000018
Type P
Source Link BioCarta
Publication Reference NA
PAG Description The complement system is part of the defense against invading cells and is composed of about twenty different proteins found in the plasma. When activated, complement proteins form a pathway of proteolytic reactions that culmites in the lysis of foreign cells. The complement system also stimulates phagocytosis of foreign cells and an inflammatory response. There are two different complement systems, the classical complement pathway initiated by antibody complexes on the cell surface, and an altertive complement pathway that is initiated without antibodies.
Species Homo sapiens
nCoCo Score 2,204
Base PAG ID WAG000018
Human Phenotyte Annotation
Curator PAGER curation team
Curator Contact PAGER-contact@googlegroups.com
Gene ID Gene symbol Gene name RP_score
Gene A Gene B Source SCORE

Gene A Gene B Mechanism Source
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